CHEMISTRY-2020

Molecular diversity

Molecular diversity, of each natural and synthetic materials, provides a valuable source of compounds for identifying and optimizing new drug leads. Through the quickly evolving technology of combinatorial chemistry, it is now currently  to produce libraries of small molecules to screen for novel bioactivities. The ‘ molecular diversity spectrum ’. In qualitative terms, diversity is viewed as a spectrum ranging from a TOS to the synthesis of all possible molecular entities. Traditional combinatorial chemistry, wherever diversity primarily arises from building block variation, and DOS, where skeletal diversity is also incorporated, produce compound collections between these two extremes.